FcRn, Alb1; Albza
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Fig.1 Detection of ALB expression in serum by blood biochemical analysis (n=4).
Abbr. HO, homozygous; WT, wild type.
Fig.2 Detection of hALB (A) and rALB (B) expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Fig.3 Expression characterization of hFCRN in hALB/hFCRN dKI rat by Western blot. (Arrow indicates expected molecular weight and asterisk indicates a nonspecific band)
Fig.4 Blood concentration curve of test articles in hFcRn/hALB dKI rats.
In hFcRn/hALB dKI rats, the half-life time: TA-N434A > TA-YTE > TA. (In cooperation with the third party)
Fig.5 PK study of Keytruda in hALB/hFCRN dKl rat. (n=3/time point/group)
Fig.6 PK study of Cyramza in hALB/hFCRN dKI rat. (n=3/time point/group)
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