hIL17A

Background : C57BL/6Smoc

Catalog : NM-HU-00042

Strain Name :

C57BL/6Smoc-Il17atm1(hIL17A)/Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Il17a gene was replaced by human IL17A gene.

Validation Data

image.png

Fig1. Detection of IL-17A expression in Large Intestine by RT-PCR. Wild type: only one band at 100 bp with primers F1/R1(mIl-17a);Homozygous: only one band at 121 bp with primers F2/R2(hIL-17A); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

IL17A.png

Fig2. Expression of human IL17A in cell supernatant derived from splenocytes  of IL17A-HU homozygous mice is detected by Elisa.

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