hL1CAM

Background : C57BL/6Smoc

Catalog : NM-HU-220414

Strain Name :

C57BL/6Smoc-L1camtm(hL1CAM)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse L1cam gene was replaced by human L1CAM gene.

Validation Data

image.png

Fig.1 Detection of L1CAM expression in cerebellum by RT-PCR. 

Wild type: only one band at 313 bp with primers F1/R1(mL1cam);

Homozygous: only one band at 305 bp with primers F2/R2(hL1CAM).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human L1CAM expression in brain in hL1CAM mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

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