MAp19, MASP-2
活体
Fig1. Detection of MASP2 expression in liver by RT-PCR.
Wild type: only one band at 479 bp with primers F1/R1(mMasp2);
Homozygous: only one band at 338 bp with primers F2/R2(hMASP2);
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Detection of hMASP2 expression in liver in HO hMASP2 mice by western blot.
Abbr. HO, homozygous; WT, wild type.
Note: The anti-human MASP2 antibody cross-reacted with mouse MASP2 and humanized MASP2.
Fig3. Detection of hMASP2 expression in liver in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig4. Detection of hMASP2 expression in kidney in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig5. Detection of IgA expression in liver in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig6. Detection of IgA expression in kidney in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig7. No obvious pathological features were found in liver in HO hMASP2 mice.
Abbr. HO, homozygous; WT, wild type.
Fig8. No obvious pathological features were found in kidney in HO hMASP2 mice.
Abbr. HO, homozygous; WT, wild type.
Fig9. Detection of mC3 expression in serum by ELISA.
Abbr. HO, homozygous; WT, wild type.
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