hRSPO1

Background : C57BL/6Smoc

Catalog : NM-HU-225041

Strain Name : C57BL/6Smoc-Rspo1tm1(hRSPO1)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Rspo1 gene was replaced by human RSPO1 gene.

Validation Data

image.png

Fig1. Detection of RSPO1 expression in lung by RT-PCR. 

Wild type: only one band at 183 bp with primers F1/R1 (mRspo1);

Homozygous: only one band at 210 bp with primers F2/R2 (hRSPO1);


Abbr. M, DNA marker; HO, homozygous;  WT, wild type.

image.png

Fig2. Detection of human and mouse RSPO1 expression in liver homogenate by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. The human and mouse RSPO1 ELISA kit cross-reacted with mouse RSPO1 and humanized RSPO1.

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