Strain Model Specification

hSERPINC1

Strain Name C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc
Catalog Number NM-HU-225075
Genetic Background C57BL/6Smoc
Gene Symbol Serpinc1
Synonyms At3, At-3, ATIII, AI114908
NCBI ID 11905 ↗
MGI ID 88095 ↗
Ensembl ID ENSMUSG00000026715 ↗
Strain State Repository Live

Validation Data

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Fig1. Detection of SERPINC1 expression in liver by RT-PCR. 

Wild type: only one band at 250 bp with primers F1/R1 (mSerpinc1);

Homozygous: only one band at 374 bp with primers F2/R2 (hSERPINC1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig2. Detection of hSERPINC1(A) and mSERPINC1(B) expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

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Fig3. Detecion of coagulation time in hSERPINC1 knockin mice by APTT(n=3). 

Abbr. HO, homozygous; WT, wild type.