Lum-2A-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-210447

Strain Name : C57BL/6Smoc-Lumem1(2A-CreERT2)Smoc

Gene Summary

Gene Name

Model Description

2A-CreERT2 expression cassette was knocked into the Lum gene stop codon site.

Validation Data

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Fig1. Cre mediated recombination in Cornea of LumCreERT2/+;Rosa26tdTomato/+ mouse. (ep, epithelium; st, stroma.)

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Fig2. Cre mediated recombination in skin of LumCreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig3. Detection of tdTomato(red) in various tissues of LumCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: cornea, skin, stomach, small intestine, colon, spleen and adrenal gland. A few cells expressed in spinal cord, salivary gland, thymus. Tissues that unexpressed include brain, heart, lung, liver, brown fat, pituitary, kidney, pancreas and testis. (9-week old, male) (For more detailed information please contact our technical advisor.) 

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