MC38-hPD-L1

Background : MC38

Catalog : NM-S13-TM01

Strain Name :

MC38-Cd274em1(hPDL1)/Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Cd274(also known as PD-l1) gene was replaced by human PDL1 gene.

Validation Data

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Figure 1. hPDL1 expression in wild-type MC38 and MC38-hPDL1 cell lines.

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Figure 2. Tumor growth curve of MC38-hPDL1 syngeneic model (n=3).

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Figure 3. The expression of hPDL1 in humanized modified tumors by FACS.

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Figure 4. Antitumor activity of Tencentriq and another anti-PDL1 antibody (n=8).

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