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Slc17a6-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-190011

Strain Name : C57BL/6Smoc-Slc17a6^{em2(CreERT2)Smoc}

Gene Summary

Gene Name

Synonyms :
DNPI, Vglut2, 2900073D12Rik
NCBI ID :
140919
MGI ID :
2156052
Ensembl ID :
ENSMUSG00000030500
Strain State :
精子冻存

Model Description

This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

Validation Data

Fig1. Expression Pattern of Tomato in Slc17a6-CreERT2 +/-;R26- tdTomato+/- mice.

CreERT2-mediated recombination in excitatory glutamatergic neuron cell bodies of Slc17a6-CreERT2+/-; R26-tdTomato+/- mice. Slc17a6-CreERT2 mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons.

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