Slc17a6-IRES-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200087

Strain Name : C57BL/6Smoc-Slc17a6em1(IRES-iCre)Smoc

Gene Summary

Gene Name

Model Description

A IRES-iCre expression cassette was knocked into the Slc17a6 gene stop codon site.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of Slc17a6Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex, hippocampus and thalamus derived from Slc17a6Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Cre-mediated recombination in the retina of Slc17a6Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the retinal ganglion cell layer derived from Slc17a6Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 3 Detection of tdTomato(red) in various tissues of Slc17a6Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the cortex, hippocampus, striatum and thalamus. TdTomato can also be detected in individual cells of the retinal ganglion cell layer and extranet layer, pituitary gland, heart, kidney, testis, epididymis, brown fat, thymus, spleen, stomach, skeletal muscle, intestine, colon, salivary gland and pancreas islet. Tdtomato expression can not be observed in the lung, liver or skin. (For more detailed information please contact our technical advisor.)


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