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Home / Toolbox of Mice / Find Cre / Slc6a4-Cre

Slc6a4-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200115

Strain Name : C57BL/6Smoc-Slc6a4em1(iCre-pA)Smoc

Gene Summary

Gene Name
  • Synonyms :

    Htt, Sert, 5-HTT, AI323329

  • NCBI ID :

    15567

  • MGI ID :

    96285

  • Ensembl ID :

    ENSMUSG00000020838

  • Strain State :

    Sperm cryopreservation

Model Description

A iCre-pA expression cassette was knocked into the Slc6a4 gene start codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the neurological disorders such as addiction and depression.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of Slc6a4Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex, thalamus and olfactory bulb of Slc6a4Cre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of Slc6a4Cre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the cortex, thalamus, heart, bronchi, liver, stomach, salivary gland, skin, testis, kidney, thymus, spleen, pancreas, intestine and colon. Tdtomato expression can not be detected in the retina or muscle. (For more detailed information please contact our technical advisor.)


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