This tamoxifen-inducible tyrosine-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Tyr(tyrosine) gene by CRISPR/Cas9 gene editing technology.
Validation Data
Fig1 CreERT2-mediated recombination in basal epidermal melanocytes of Tyr-CreERT2+/- ；R26 tdT+/- mice.
