Wap-IRES-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200064

Strain Name : C57BL/6Smoc-Wapem1(IRES-Cre-WPRE-polyA)Smoc

Gene Summary

Gene Name

Model Description

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Wap gene stop codon site.

Validation Data

Wap-IRES-Cre-1.png

Fig.1 Cre-mediated recombination in the mammary gland of female WapCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the mammary gland epithelial cells of the lactating WapCre/+; Rosa26tdTomato/+ mouse. 

Wap-IRES-Cre-2.png

Fig.2 Detection of tdTomato(red) in various tissues of WapCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the some cells of salivary glands and mammary glands of the lactating mouse. Tdtomato can not be detected in the brain, thymus, pituitary gland, heart, lung, liver, stomach, kidney, brown fats, colon, pancreas, muscle, testis and epididymis. (For more detailed information please contact our technical advisor.)

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