Humanized Models

Humanized mouse models are experimental animals that have been genetically modified or implanted with human cells, tissues, or genes. These models are used in biomedical research to study human diseases, test therapies, and understand biological processes. By incorporating human biological components into mice, researchers can investigate how diseases develop, how the immune system responds to treatments, and how drugs interact with human cells in a controlled laboratory setting. Humanized mouse models are valuable tools for advancing medical research and drug development, providing insights that can potentially lead to new treatments and therapies for human diseases.

Target Classifications

Tumor Targets

Immune Checkpoints

Complements

Cytokines

Cytokine Receptors

Metabolic Targets

Viral Infection Receptors

Other Targets

Cytokine Receptors

GenoBioTX has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.