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Immune-Related Mice

Immune-Related Mice

Mice with defective adaptive immunity including nude, SCID and NOD-SCID mice, can effectively control common opportunistic agents such as Pseudomonas spp., until myeloablative effects from irradiation or other interventions eliminate their innate immunity as well. The effects of ionizing radiation on other tissues, and on developing or proliferating cells, influence morbidity and mortality of research mice.

Target Classifications

Immunodeficient

Humanized Drug Targets

Cytokine Reporters

Inducible Cell Ablation

Cell-specific Reporter

Humanized Drug Targets

Humanized mice of drug target genes, such as humanized mice of immune checkpoint genes, for drug screening and drug efficacy evaluation, helping accelerate the development of drugs.

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  • h4-1BB(2) NM-HU-190077 1

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