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Toolbox of Mice

We provide researchers a wide range of Cre recombinase, reporter gene, and Cas9-related mice, thesemouse models provide powerful tools for investigating gene function, regulatory elements, anddisease mechanisms in yivo, contribuung to advances in biomedical and genetic research.

Target Classifications

Fluorescent & Other Reporters

Reporters

Rat models carrying knock-in or transgenic fluorescent reporter genes for gene expression profiling and visual analysis, protein subcellular localization, and genetic lineage tracing.

Find Cre

Cre mice are genetically engineered laboratory models used to activate or deactivate specific genes in targeted tissues, enabling precise studies of gene function and disease mechanisms

Tet-regulated

The tetracycline (tet)-regulated expression system permits the inducible overexpression of protein-coding. The protein expression is commonly achieved by crossing mice carrying a TRE promoter cassette transgene with mice carrying a tet transactivator transgene resulting in progeny carrying both genetic components.

CRISPR/Cas knockins

CRISPR-Cas is a versatile genome editing technology for studying the functions of genetic elements. To broadly enable the application of CRISPR-associated nucleases(cas9, dcas9, Cas13d) in vivo, we established a set of Cre-dependent Cas knockin mouse models.