Humanized Models

Humanized mouse models are experimental animals that have been genetically modified or implanted with human cells, tissues, or genes. These models are used in biomedical research to study human diseases, test therapies, and understand biological processes. By incorporating human biological components into mice, researchers can investigate how diseases develop, how the immune system responds to treatments, and how drugs interact with human cells in a controlled laboratory setting. Humanized mouse models are valuable tools for advancing medical research and drug development, providing insights that can potentially lead to new treatments and therapies for human diseases.

Target Classifications

Tumor Targets

Immune Checkpoints

Complements

Cytokines

Cytokine Receptors

Metabolic Targets

Viral Infection Receptors

Other Targets

Viral Infection Receptors

Many of the viral pathogens that cause infectious diseases in humans have a highly restricted species tropism, making the study of their pathogenesis and the development of clinical therapies difficult. The construction of humanized viral infection receptor knockin mice will greatly facilitated researchers’ abilities to study host responses to viral infections in a cost effective and ethical manner.