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U-GEMMs

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Mice

hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd8aem1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210373

hPD-1(NM-HU-00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice

Mice

hTNFSF14

Strain Name:C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225069

The endogenous mouse Tnfsf14 gene was replaced by human TNFSF14 gene.

Mice

Zbtb46-2A-CreERT2

Strain Name:C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18021

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200188

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hALB

Strain Name:C57BL/6Smoc-Albem3(ALB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200003

The endogenous mouse Alb gene was replaced by human ALB gene.

Mice

hBTLA(BALB/c)

Strain Name:BALB/cAnSmoc-Btlaem1(hBTLA)/Smoc
Strain State:Developing | Cat. NO.:NM-HU-2000044

The endogenous mouse Btla gene was replaced by human BTLA gene.

Mice

hB7H4

Strain Name:C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hB7H3/hCD28

Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210353

hB7-H3(NM-HU-00107) was crossed with hCD28(NM-HU-190011) to generate hB7H3/hCD28 mice.

Mice

Brca1-Flox

Strain Name:C57BL/6Smoc-Brca1tm1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-18007

These Brca1 flox mice possess loxP sites flanking exons 5 . When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Adgre1-2A-CreERT2

Strain Name:C57BL/6Smoc-Adgre1em1(2A-CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190025

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

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