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U-GEMMs

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Mice

Nphs2-CreERT2

Strain Name：C57BL/6Smoc-Nphs2tm1(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00128

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

Mice

hCYP2D6

Strain Name：C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215024

The endogenous mouse Cyp2d22 gene was replaced by human CYP2D6 gene.

Mice

Abcb10-Flox

Strain Name：C57BL/6Smoc-Abcb10em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Abcb10 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb10 gene.

Mice

Il7-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il7em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00092

A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of mouse Il7 gene.

Mice

hPD-L1/hSEMA4D

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Sema4dem1(hSemA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190034

hPD-L1(NM-HU-00062) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-L1/hSEMA4D.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

hTNFR2/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220041

hTNFRSF1B(NM-HU-190010)，hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed together to generate hTNFRSF1B/hPD-1/hPD-L1 mice.

Mice

Fah-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fahem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-NSG-004

Exon 3 of Fah gene was deleted to generate Fah knockout mice.

Mice

Tph1-2A-mCherry

Strain Name：C57BL/6Smoc-Tph1em(2A-mCherry)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220182

2A-mCherry expression cassette was knocked into the Tph1 gene stop codon site.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

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