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U-GEMMs

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Mice

hIL4-Tg(NMG)(2)

Strain Name：NOD-PrkdcscidIl2rgem2Tg(hIL4)Smoc
Strain State：Developing | Cat. NO.：NM-KI-220132

These transgenic mice carry humanized IL4.While hIL4-Tg(NMG)(Stock No.NM-KI-215004) mice function similarly to hIL4-Tg(NMG)(2) mice, for more detailed information please contact our technical advisor.

Mice

Il17c-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

Trpv1-IRES-Cre

Strain Name：C57BL/6Smoc-Trpv1em1(Myc-IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200139

A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.

Mice

A2ml1-Flox

Strain Name：C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

Mice

hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210414

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

Mice

hPDGFRA

Strain Name：C57BL/6Smoc-Pdgfratm1(hPDGFRA)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200250

The endogenous mice Pdgfra gene was replaced by human PDGFRA gene.

Mice

hPD-L1/hVISTA

Strain Name：C57BL/6Smoc-Visrem1(hVSIR)Cd274em1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

Gba-Flox

Strain Name：C57BL/6Smoc-Gbaem2(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200051

These mice carry loxP sites flanking exon 8-11 of Gba gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gba gene.While Gba-Flox(2)(Stock No.NM-CKO-200179）mice carrying the loxP sites flanking exon 6-8 of Gba gene.

Mice

Bmi1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Bmi1em1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200095

A IRES-CreERT2 expression cassette was knocked into the Bmi1 gene stop codon site.

Mice

Ctnnb1-Flox

Strain Name：C57BL/6Smoc-Ctnnb1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200154

These mice carry loxP sites flanking exon 2-6 of Ctnnb1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ctnnb1 gene.

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