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U-GEMMs

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Mice

hTFR1

Strain Name:C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215059

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Mice

hOX40

Strain Name:C57BL/6Smoc-Tnfrsf4em1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00041

The endogenous mouse Tnfrsf4(Ox40) gene was replaced by human TNFRSF4(OX40) gene. While hOX40(2)(Stock No.NM-HU-00078) mice function similarly to hOX40 mice,for more detailed information please contact our technical advisor.

Mice

hTSLP

Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000064

The endogenous mouse Tslp gene was replaced by human TSLP gene.

Mice

hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00100

hPD-1(NM-HU-00015) was crossed with hPD-L1(NM-HU-00062)to generate hPD-1/hPD-L1 mice

Mice

H11-pT3(b)-hIL15-Flag

Strain Name:C57BL/6Smoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220128

pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA expression cassette was knocked into the the lgs2 (H11) locus.

Mice

HBV-Tg

Strain Name:B6.Cg-Tg(HBV)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-00003

Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.

Mice

hANGPTL3(4)

Strain Name:C57BL/6Smoc-Angptl3em1(hANGPTL3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210036

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

hOX40/Cd8a-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Tnfrsf4em1(hTNFRSF4)Cd8aem1(V5-IRES-luc-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210375

hOX40(NM-HU-00041) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hOX40/Cd8a-IRES-Akaluc-2A-EGFP mice.

Mice

hAQP4

Strain Name:C57BL/6Smoc-Aqp4em1(hAQP4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210001

The endogenous mice Aqp4 gene was replaced by human AQP4 gene

Mice

hSDC1

Strain Name:C57BL/6Smoc-Sdc1em1(hSDC1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000026

The endogenous mouse Sdc1 gene was replaced by human SDC1 gene.

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